Author: Aldiyarbek Nurlan
Editor: Merentsova Anastasia
The researchers found that fat build-up in men and women strongly affects the activity of 162 different genes found in adipose tissue. Some of these identified genes are already associated with pathological conditions such as type 2 diabetes and cardiovascular disease.
The study identified thousands of genes localized in adipose tissue, however, there were quite significant differences in 162 genes, based on the analysis of approximately 3000 human samples collected from different regions.
Scientists also identified six specific genes that had a significant impact on the regulation of adipose tissue activity, which makes it possible to focus on these six genes as potential therapeutic targets.
Genes identified by scientists responsible for adipose tissue can affect the severity of the above diseases and the differences in the therapeutic effect provided in men and women. According to the researchers, the results obtained by them will play a critical role in the search for an effective targeted therapy that has a therapeutic effect on a specific affected area, and may differ in men and women.
Source: https://www.sciencedaily.com/releases/2020/09/200928093746.htm
