Author: Aldiyarbek Nurlan
Editor: Merentsova Anastasia
The human genome provides a complete blueprint for human genes, the human proteome identifies the individual building blocks of life - proteins. Proteins interact to form everything from life-threatening diseases to the cellular structure in our bodies.
Now that 90 percent of the proteins in the human body are mapped, researchers have a deeper understanding of how individual proteins interact to influence human health, which provides insight into disease prevention, the researchers said.
This study could have implications for scientists studying potential treatments for COVID-19. COVID-19, for example, involves two proteomes, the SARS-CoV-2 virus and the proteomes of infected cells, both of which are likely to interact, modify, and alter each other's function. Understanding this relationship could explain why some cells and humans are more resistant to COVID-19 while others are more vulnerable.
Since many human diseases result from protein changes, proteome mapping strengthens the basis for disease diagnosis, prognosis of outcomes, and treatment.
"Knowing which proteins are key to protect against disease can provide information for the development of new therapies," the researchers say.
Source: https://www.sciencedaily.com/releases/2020/10/201019133648.htm
