Author: Vishnevskaya Karina
Copy editor: Kigbayeva Kamila
In a case-control retrospective cross-sectional study, data from electronic medical records of 31 male patients who showed foveal cavitation on optical coherence tomography in the spectral region were included.
Men were divided into groups, one of the groups was assigned 5-ARIs of unknown origin in drugs of 5-alpha-reductase inhibitors, and in the second group of patients with macular abnormalities, 5 ARIs of well-known specific origin. Optical coherence tomography showed a spectrum of diseases from tiny foveal cavitation to an impending macular hole. Of the total number of male patients, 8 out of 10 had no symptoms.
Data suggest that macular abnormalities associated with 5-ARI are characterized by cystoid abnormalities and foveal cavitation in male patients, which can progress to an external foveal defect and macular hole.
Source: https://www.researchgate.net/