Editor: Bolysbek Dana
Author: Tulkibaeva Nursulu
Chronic stress can affect tissue homeostasis, but the mechanisms by which these changes occur are largely unknown.
American scientists, led by Ya-Chieh Hsu from Harvard University, in their recent study found out the mechanism of influence of stress factors on hair loss, the experiment was carried out on mice.
The study found that corticosterone, a hormone secreted by mice during stress, affects the regulation of hair follicle stem cells, thereby inhibiting hair growth. In humans, a hormone similar to mouse corticosterone is produced by the adrenal cortex called cortisol.
Scientists have found that the action of the stress hormone blocks the synthesis of the protein GAS6, which is responsible for the proliferation of hair follicle stem cells, this blockage puts the hair follicles into a dormant stage. Conversely, restoration of GAS6 synthesis activates new hair growth.
Based on the results obtained, the problem of hair loss associated with chronic stress may be replenished with new treatments.
