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How can IUDs prevent endometrial cancer in high-risk women?

A study by scientists from the University of Queensland has shown that a hormonal IUD can be an effective treatment option for precancerous endometrial conditions.

Editor: Bolysbek Dana

Author: Tulkibaeva Nursulu


Uterine corpus cancer, or endometrial cancer, is a malignant neoplasm of the uterine mucosa. The disease most often affects postmenopausal women, but recently there is a trend towards its "rejuvenation".

            The standard and effective treatment for endometrial cancer is total hysterectomy, in which the uterus, cervix, fallopian tubes, and ovaries are removed.

            Scientists from the University of Queensland have proposed an alternative treatment option for women who are contraindicated to surgery or want to preserve fertility. An intrauterine device (IUD) with levonorgestrel was suggested as an option and was found to be effective in 43 percent of women in the study.

            "Examples of women who might benefit from the IUD used in the study are women with severe obesity and other serious pathologies such as heart, kidney or lung disease, another option when a woman wants to maintain her fertility," said lead researcher Dr. Andreas Obermayr.

            Next, the researchers plan to find out why the IUD is ineffective in the other 60% of women who participated and to develop new molecular targets for cancer treatment.