Editor: Aigerim Akhmetova
Author: Bolysbek Dana
Early studies of regional health systems have shown that COVID-19 is associated with a higher risk of AKI. To provide more reliable data, a team led by Ziyad al-Ali, MD (VA Saint Louis Health Care System and Washington University in St. Louis), examined data from 5,216 U.S. veterans hospitalized with COVID-19 from March to July.
Among the main findings:
1,655 (32%) veterans had AKI: 58%, 13% , and 16% with stage 1, 2, and 3 AKI, respectively.
201 (12%) of these patients received renal replacement therapy (dialysis).
In 80% of patients with AKI, it developed within 1 day after hospitalization, and 47% did not fully recover kidney function by the time of discharge.
Older age, black race, male gender, obesity, diabetes, hypertension, and decreased kidney function were significant predictors of AKI during hospitalization with COVID-19.
AKI was associated with a higher probability of requiring mechanical ventilation and a longer hospital stay.AKI was associated with a 6-7-fold increased risk of death, and this Association was stronger in black veterans.
The rates of AKI had significant geographical variability (from 10% to 56%), and higher rates were observed in regions where more black veterans visited hospitals.
Between March and July 2020, the incidence of AKI decreased, while the proportion of stage 3 AKI and AKI requiring renal replacement therapy decreased.
"This is the first national study of AKI in COVID-19 that has shown us that AKI is very common," Dr. al - Ali said. "It was also striking to see that almost half of veterans with AKI left the hospital with an unresolved AKI - meaning they are likely to need long-term follow-up and care, they are also likely to suffer long-term consequences for life."
Source: https://medicalxpress.com/news/2020-11-covid-associated-kidney-injury-ve...
