Author: Aldiyarbek Nurlan
Editor: Merentsova Anastasia
Scientists conducted a study of the venom of 28 spiders, of which the most promising was the venom of the Venezuelan tarantula - the pinkfoot goliath.
The authors of the work found that two peptides isolated from tarantula venom inhibit the most important ion channels underlying the body's pain response mechanism, with one being especially effective in weakening the nervous sensitivity of the bladder and colon and almost stopping chronic visceral pain in an IBS model.
Pain in bowel disease is difficult to control and affects about 20 percent of the world's population. Modern drugs are not able to effectively relieve pain due to the impossibility of using a higher dosage due to side effects.
“Our goal was to find more specialized pain blockers that were more potent and targeted at sodium channels of pain without affecting the heart or other organs, and we found them in the venom of the pinkfoot goliath spider.” , - summed up the researchers.
Source: https://www.sciencedaily.com/releases/2020/09/200921100347.htm
